Medical Treatment of Graves' Disease

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Medical Treatment of Graves’ Orbitopathy

▼ The medical treatment of Graves’ orbitopathy (GO) is usually reserved to moderate to severe disease. Steroids have been widely employed and possess anti-inflammatory activity, but about 20–30 % of patients are not responsive and about 20 % present with disease recurrence. Immunosuppressive therapy alternative to corticosteroids may target the different antigens involved in pathogenic mechanis...

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Medical Treatment of Graves’ Orbitopathy

▼ The medical treatment of Graves’ orbitopathy (GO) is usually reserved to moderate to severe disease. Steroids have been widely employed and possess anti-inflammatory activity, but about 20–30 % of patients are not responsive and about 20 % present with disease recurrence. Immunosuppressive therapy alternative to corticosteroids may target the different antigens involved in pathogenic mechanis...

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Prognostic Factors in the Relapse of Graves’ Disease Following Treatment with Antithy-roid Drugs

Background: Patients with Graves’ disease exhibit a considerable rate of relapse after treatment with antithyroid drugs and require ablative therapy. Objective: The purpose of this study was to evaluate variables which can be used as prognostic factors in predicting the outcome of Graves’ disease after treatment with antithyroid drugs. Methods: Age, sex, duration of antithyroid drug therapy, pr...

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Retrospective study of clinical course and treatment response in Graves’ disease [Persian]

In this report, the clinical course and treatment response of 210 patients with Grawes’ disease referred to the research institute for nuclear medicine were studied. The disease was more common in 3rd and 4th decades and more frequent in women (F/M=4). Treatment response with antithyroid drugs was about 50%, whereas 80% of the patients treated by I-131 showed positive response. There was ...

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[Practical diagnosis and treatment of Graves' disease].

1.診断 (1)Basedow 病を疑う Basedow 病診断の第 1 歩はもちろん疑うことであ る.疑うきっかけは,体重減少,疲れやすい,動悸, 手指振戦,微熱,頻脈,低コレステロール血症など何 らかの代謝亢進を思わせる症状である.眼球突出は特 徴的な症状であるが,眼症状が軽いケースに気づくに はかなり経験が必要である.びまん性甲状腺腫もわか りにくいケースも多い. (2)診断のための検査 1)TSH と甲状腺ホルモン:甲状腺機能亢進症(甲状 腺中毒症)の診断は血液検査だけでよい.スクリーニ ングとして測定するのは TSH と遊離 T4 の 2 つでよ い.この 2 つが正常であれば甲状腺疾患は現在の症状 には関係していないと言い切れる.甲状腺疾患による 甲状腺機能亢進症であれば TSH は 0.01 μU ml 以下 に抑制され,遊離 T4 が上昇している.遊離 T4 が上昇 ...

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ژورنال

عنوان ژورنال: Postgraduate Medical Journal

سال: 1932

ISSN: 0032-5473

DOI: 10.1136/pgmj.8.81.247